ANFD – AGITATED NUTSCHE FILTER-DRYERS
FOR PILOT PLANT AND COMMERCIAL SCALE PRODUCTION
AT A GLANCE
Everyday our technology is assisting hundreds of pilot and production facilities around the world to reliably manufacture and bring their products to the market faster. PSL filter-dryer systems are being used in a wide range of industries such as pharmaceuticals, fine chemicals and precious metals.
Our ANFD production systems were developed to efficiently wash and isolate solids in the most complex chemical synthesis processes and challenging production environments. Our solutions are designed to overcome well-known challenges faced by manufacturers when using traditional production methods, such as Büchner filtration and oven tray-drying.
Each of our filter-dryer consists of an agitated vessel designed to work under vacuum and under pressure. Its vessel can be made of either stainless steel or alloy 22 and can be coated with specific materials such as PFA (perfluoroalkoxy alkane). It is also equipped with a heated jacket and heated agitator for efficient product drying and mixing.
AT A GLANCE
Everyday our technology is assisting hundreds of pilot and production facilities around the world to reliably manufacture and bring their products to the market faster. PSL filter-dryer systems are being used in a wide range of industries such as pharmaceuticals, fine chemicals and precious metals.
Our ANFD production systems were developed to efficiently wash and isolate solids in the most complex chemical synthesis processes and challenging production environments. Our solutions are designed to overcome well-known challenges faced by manufacturers when using traditional production methods, such as Büchner filtration and oven tray-drying.
Each of our filter-dryer consists of an agitated vessel designed to work under vacuum and under pressure. Its vessel can be made of either stainless steel or alloy 22 and can be coated with specific materials such as PFA (perfluoroalkoxy alkane). It is also equipped with a heated jacket and heated agitator for efficient product drying and mixing.
INDUSTRY APPLICATIONS
| INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
|---|---|---|---|---|
| Pharmaceuticals | Process optimisation | Filtration | Suspension | API drugs |
| Chemicals | Pilot development | Separation | Slurry | Intermediates |
| Food | Pre-clinical & clinical | De-watering | Wet cake | Raw materials |
| Material sciences | GMP batch | Re-slurry | Powder | Excipients |
| Synthesis | Commercial production | Washing | Semi-solids | Reagents |
| Special processes | Mixing | Catalysts | ||
| Sampling | Precious metals | |||
| Drying | Graphene, Lithium | |||
| Discharge |
INDUSTRY APPLICATIONS
| INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
|---|---|---|---|---|
| Pharmaceuticals | Process optimisation | Filtration | Suspension | API drugs |
| Chemicals | Pilot development | Separation | Slurry | Intermediates |
| Food | Pre-clinical & clinical | De-watering | Wet cake | Raw materials |
| Material sciences | GMP batch | Re-slurry | Powder | Excipients |
| Synthesis | Commercial production | Washing | Semi-solids | Reagents |
| Special processes | Mixing | Catalysts | ||
| Sampling | Precious metals | |||
| Drying | Graphene, Lithium | |||
| Discharge |
VESSEL SIZES
| Filtration Area | 0.05m2 | 0.125m2 | 0.3m2 | 0.6m2 | 1.0m2 |
| Filter Cake Volume Range | 1 to 10L | 2.5 to 50L | 6 to 120L | 12 to 240L | 50 to 400L |
| Filter Cake Height Range | 20 to 150 mm | 20 to 200 mm | 20 to 400 mm | 20 to 400 mm | 50 to 400 mm |
| Max Liquid Volume | 20L | 100L | 270L | 600L | 1000L |
VESSEL SIZES
| Filtration Area | 0.05m2 | 0.125m2 | 0.3m2 | 0.6m2 | 1.0m2 |
| Filter Cake Volume Range | 1 to 10L | 2.5 to 50L | 6 to 120L | 12 to 240L | 50 to 400L |
| Filter Cake Height Range | 20 to 150 mm | 20 to 200 mm | 20 to 400 mm | 20 to 400 mm | 50 to 400 mm |
| Max Liquid Volume | 20L | 100L | 270L | 600L | 1000L |
FEATURES & BENEFITS
- Slurry filtration
- Product washing
- Re-slurry
- Vacuum drying
- Product sampling
- Product discharge
PSL’s strength lies in our comprehensive knowledge of the GMP regulations combined with our practical experience and knowledge of a wide range of manufacturing workflows.
Our PSL filter-dryers provide optimum levels of safety and quality and can be manufactured to comply with various industry practices (cGMP, GAMP, etc.), directives (ATEX, etc.), regulations (21 CFR Part 11, etc.) and initiatives (PAT, etc.) from industry regulators such as the FDA.
At Powder Systems, we understand that selecting the right processing technology is critical to scale-up your process and ensure your ultimate production success.
Our established filtration and drying range is globally recognised to streamline the most complex scale-up process developments, from early R&D activities to GLP batches, pilot plant and ultimately GMP commercial production.
Our filter-dryer portfolio will allow you to perform scale-up and scale-down studies and maintain – at every scale – your various process objectives (e.g. product quality, product yield, batch consistency, etc.) and production parameters (e.g. filtration time, washing time, drying time, etc.).
At PSL, we understand that your product is extremely valuable and that you must maximize your production yield in order to remain competitive in your market. The core features of our filter-dryers were designed keeping this crucial requirement in mind.
Upon process completion inside a PSL filter-dryer, your valuable product can be recovered very simply by utilising the PSL agitator to automate the discharge process. Subsequently, the remainder of your batch – also called product heel – can be collected following the ‘’Direct Heel Recovery’’ method originally pioneered by PSL in the industry several decades ago.
This method has proven to be the most efficient for high yield productivity and it consists of manually raking the product heel into a PSL high containment off-loading glovebox (ergonomically designed and integrated by PSL). Thus ensuring a full product recovery under safe conditions for your operators, product and environment.
Being one of the early pioneers of containment technology, PSL can enhance its filtration & drying solution range with unique high-containment systems.
Numerous industrial filtration & drying processes require to integrate containment technology in order to protect operators from highly toxic compounds or/and to protect sensitive products from any harmful production environment.
PSL containment systems can be integrated to our full filter-dryer range to allow you to complete a large range of process operations while protecting your operators’ safety and safeguarding the integrity of your product.
NUTSCHE FILTER DRYER SERVICES
RESOURCES
HOW CAN PSL HELP WITH YOUR NEXT PROJECT?
Contact us to see how PSL can assist on your next project or if you simply have a question for us. A PSL representative will respond within one working day.
HOW CAN PSL HELP WITH YOUR NEXT PROJECT?
Contact us to see how PSL can assist on your next project or if you simply have a question for us. A PSL representative will respond within one working day.
