SimpleFilter™
PILOT PLANT NUTSCHE FILTER & DRYER
AT A GLANCE
The SimpleFilter™ is a cost-effective and user-friendly solution allowing efficient nutsche filtration and drying of small and pilot scale batches. It is a compact and mobile system that can be easily moved throughout different production areas within a same facility.
The SimpleFilter™ was developed to overcome well-known production challenges faced by manufacturers when using traditional production methods such as Büchner filtration and oven tray-drying. It is the ideal technology to successfully complete scale-up and scale-down activities and obtain predictive performance results.
The SimpleFilter™ consists of a single plate pressure & vacuum filter-dryer vessel equipped with a glove-bag containment system allowing simple and effective product discharge under nitrogen purge. Its vessel is available in different materials hence suiting a broad range of chemical processes.
AT A GLANCE
The SimpleFilter™ is a cost-effective and user-friendly solution allowing efficient nutsche filtration and drying of small and pilot scale batches. It is a compact and mobile system that can be easily moved throughout different production areas within a same facility.
The SimpleFilter™ was developed to overcome well-known production challenges faced by manufacturers when using traditional production methods such as Büchner filtration and oven tray-drying. It is the ideal technology to successfully complete scale-up and scale-down activities and obtain predictive performance results.
The SimpleFilter™ consists of a single plate pressure & vacuum filter-dryer vessel equipped with a glove-bag containment system allowing simple and effective product discharge under nitrogen purge. Its vessel is available in different materials hence suiting a broad range of chemical processes.
INDUSTRY APPLICATIONS
| INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
|---|---|---|---|---|
| Pharmaceuticals | Pilot development | Filtration & De-watering | Suspension | API drugs |
| Chemicals | Scale-up | Separation | Slurry | Intermediates |
| Food | Scale-down | Re-slurry | Wet cake | Raw materials |
| Precious metals | Process prototypes | Mixing & Sampling | Powder | Excipients |
| Material sciences | Process Trials | Drying | Semi-solids | Reagents |
| Speciality processes | Process optimisation | Catalysts | ||
| General Synthesis | Pre-clinical | |||
| Hydrogenation | ||||
| Carbon Filtration | ||||
| Catalyst recovery |
INDUSTRY APPLICATIONS
| INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
|---|---|---|---|---|
| Pharmaceuticals | Pilot development | Filtration & De-watering | Suspension | API drugs |
| Chemicals | Scale-up | Separation | Slurry | Intermediates |
| Food | Scale-down | Re-slurry | Wet cake | Raw materials |
| Precious metals | Process prototypes | Mixing & Sampling | Powder | Excipients |
| Material sciences | Process Trials | Drying | Semi-solids | Reagents |
| Speciality processes | Process optimisation | Catalysts | ||
| General Synthesis | Pre-clinical | |||
| Hydrogenation | ||||
| Carbon Filtration | ||||
| Catalyst recovery |
VESSEL SIZES
| 0.125 Model | 0.3 Model | |
|---|---|---|
| Filtration Area | 0.125m2 | 0.3m2 |
| Vessel Volume | 50L | 130L |
| Typical Product Cake Volume (Process-dependant) | 6L – 38L | 15L – 90L |
| Equipment Dimensions (H x W x D) | 1,495 x 1,220 x 1,455mm | 1,510 x 1,170 x 1,490mm |
VESSEL SIZES
| 0.125 Model | 0.3 Model | |
|---|---|---|
| Filtration Area | 0.125m2 | 0.3m2 |
| Vessel Volume | 50L | 130L |
| Typical Product Cake Volume (Process-dependant) | 6L – 38L | 15L – 90L |
| Equipment Dimensions (H x W x D) | 1,495 x 1,220 x 1,455mm | 1,510 x 1,170 x 1,490mm |
UPGRADE OPTIONS
| Standard SimpleFilter | Upgrade Options | |
|---|---|---|
| Vessel Material of Construction | 316L Stainless Steel (316LSS) | PFA Coated 316LSS |
| Filtration Mesh | Polypropylene cloth mesh | 316LSS or Alloy 22 mesh |
| Agitated Vessel | No agitator | Available |
| Agitator Raise & Lower (R&L) | No agitator | Manual or Automated |
| Glove-bag for Product Discharge | Not included | Available |
| Continuous Liner Discharge Chute | Not included | Available |
| Vessel Wash & Clean-in-Place (WIP/CIP) | WIP spray-ball | CIP spray-ring available |
UPGRADE OPTIONS
| Standard SimpleFilter | Upgrade Options | |
|---|---|---|
| Vessel Material of Construction | 316L Stainless Steel (316LSS) | PFA Coated 316LSS |
| Filtration Mesh | Polypropylene cloth mesh | 316LSS or Alloy 22 mesh |
| Agitated Vessel | No agitator | Available |
| Agitator Raise & Lower (R&L) | No agitator | Manual or Automated |
| Glove-bag for Product Discharge | Not included | Available |
| Continuous Liner Discharge Chute | Not included | Available |
| Vessel Wash & Clean-in-Place (WIP/CIP) | WIP spray-ball | CIP spray-ring available |
FEATURES & BENEFITS
- Slurry filtration
- Product washing
- Re-slurry (optional agitator recommended)
- Vacuum drying
- Product sampling
- Product discharge
The SimpleFilter™ is a GMP piece of equipment ideal for multi-product applications. It is designed to allow end-users to remain agile and to quickly adapt to changing production requirements.
| FILTRATION AGILITY | DRYING AGILITY | CLEANING AGILITY |
|---|---|---|
| One modular base design | Direct heat transfer with base | GMP design / reduced product traps |
| Quick filtration media change-over | Vertical side wall heating jacket | Suitable for Reflux cleaning |
| Suitable for cloth & metallic mesh | Agitator option for drying uniformity | CIP spray-ring option |
At Powder Systems, we understand that selecting the right processing technology is critical to scale-up your process and ensure your ultimate production success. The core features of our SimpleFilter™ were designed keeping this crucial requirement in mind.
Upon batch completion inside the SimpleFilter™, your product can be easily collected by manually raking your batch from the vessel side-discharge into the glove-bag. If the agitator upgrade is purchased, the batch discharge process can be automated, with the final product heel removal only remaining manual.
Our SimpleFilter™ product range was designed to streamline your scale-up development, from feasibility studies to pilot plant and commercial production. It the perfect tool to complete scale-up and scale-down studies as it will help you maintain – at every scale – your key process objectives (product quality, product yield, batch consistency, etc.) and key production parameters (filtration time, washing time, drying time, etc.).
Being one of the early pioneers of containment technology, PSL has made all of its SimpleFilter™ models compatible with contained discharge technology.
The unique PSL glove-bag containment system was developed to allow end-users to perform safe product sampling and discharge within a nitrogen purge atmosphere for additional process safety and product integrity assurance.
Each flexible glove-bag is equipped with 2-glove arrangement to enhance ergonomics and maximise product recovery by allowing product heel-removal. A tri-clamp connection is also provided to connect the glove-bag to the chosen discharge container (via continuous liner system, split-butterfly valve, etc.)
SimpleFilter™ SERVICES
At PSL, we provide our industry partners with more than just process hardware. We take your process further together by offering a wide range of services to optimise the installation, operation and maintenance of your PSL SimpleFilter™.
By opting for our unique COPE and SERVE services, you can rest assured that you will receive and maintain a high-performing SimpleFilter™ production system, fine-tuned to your unique process requirements.
