LabMSR™ – MICROSPHERE REFINER
FOR MICROSPHERE DEPOT FORMULATION

AT A GLANCE
Due to their characteristics and properties, polymeric microspheres have traditionally been known to be difficult to process for manufacturers – especially as the batch size gradually increases as part of the microsphere product development. The unique features of our LabMSR™ were developed following a Quality-by-Design (QbD) approach, taking into account the microspheres characteristics and process behaviour.
The LabMSR™ system is a GLP piece of equipment that has been developed to enable global drug manufacturers to generally replicate, at R&D scale, some of the process benefits of PSL’s full scale production MicroSphere Refiners (MSR™).

AT A GLANCE
Due to their characteristics and properties, polymeric microspheres have traditionally been known to be difficult to process for manufacturers – especially as the batch size gradually increases as part of the microsphere product development. The unique features of our LabMSR™ were developed following a Quality-by-Design (QbD) approach, taking into account the microspheres characteristics and process behaviour.
The LabMSR™ system is a GLP piece of equipment that has been developed to enable global drug manufacturers to generally replicate, at R&D scale, some of the process benefits of PSL’s full scale production MicroSphere Refiners (MSR™).

INDUSTRY APPLICATIONS
INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
---|---|---|---|---|
Pharmaceuticals | GLP batches | De-watering | Suspension | API drugs |
Chemicals | Pre-clinical | Single pass filtration | Slurry | Polymers |
Special processes | Pilot development | Loop filtration | Wet cake | Drug depot |
Material sciences | Process optimisation | Re-slurry | Powder | Intermediates |
Scale-up/Scale-down | Washing | Semi-solids | Raw Materials | |
Drying & Freeze-drying | Excipients | |||
Discharge | Reagents |

INDUSTRY APPLICATIONS
INDUSTRIES | PRODUCTION SCALE | PROCESSES | PRODUCT FORM | INGREDIENTS |
---|---|---|---|---|
Pharmaceuticals | GLP batches | De-watering | Suspension | API drugs |
Chemicals | Pre-clinical | Single pass filtration | Slurry | Polymers |
Special processes | Pilot development | Loop filtration | Wet cake | Drug depot |
Material sciences | Process optimisation | Re-slurry | Powder | Intermediates |
Scale-up/Scale-down | Washing | Semi-solids | Raw Materials | |
Drying & Freeze-drying | Excipients | |||
Discharge | Reagents |

VESSEL SIZE
0.01 Model | |
---|---|
Typical Product Cake Volume (process-dependant) | 2.5 – 0.40L |
Maximum Liquid Volume | 2.10L |
Equipment Dimensions (L x W x H) | 1,340 x 1,030 x 1,750mm |

VESSEL SIZE
0.01 Model | |
---|---|
Typical Product Cake Volume (process-dependant) | 2.5 – 0.40L |
Maximum Liquid Volume | 2.10L |
Equipment Dimensions (L x W x H) | 1,340 x 1,030 x 1,750mm |

UPGRADE OPTIONS
Standard LabMSR™ | Upgrade Options | |
---|---|---|
De-watering Method | Suitable for Single Pass and Loop De-watering | |
Filtration Step(s) | Single Filtration (Refiner) | Dual Filtration (Scalper + Refiner) |
Drying Method | Suitable for Vacuum Drying and Freeze-Drying |

UPGRADE OPTIONS
Standard LabMSR™ | Upgrade Options | |
---|---|---|
De-watering Method | Suitable for Single Pass and Loop De-watering | |
Filtration Step(s) | Single Filtration (Refiner) | Dual Filtration (Scalper + Refiner) |
Drying Method | Suitable for Vacuum Drying and Freeze-Drying |
FEATURES & BENEFITS
LabMSR™ SERVICES
At PSL, we provide our industry partners with more than just process hardware. We take your process further together by offering a wide range of services to optimise the installation, operation and maintenance of your PSL LabMSR™.
By opting for our unique COPE and SERVE services, you can rest assured that you will receive and maintain a high-performing LabMSR™ production system, fine-tuned to your unique process requirements.
RESOURCES

HOW CAN PSL HELP WITH YOUR NEXT PROJECT?
Contact us to see how PSL can assist on your next project or if you simply have a question for us. A PSL representative will respond within one working day.
HOW CAN PSL HELP WITH YOUR NEXT PROJECT?
Contact us to see how PSL can assist on your next project or if you simply have a question for us. A PSL representative will respond within one working day.